Effect of palm oil on the lipid profile of consumers with normal cholesterol level
Author
Gómez S., Marcela
Velez Van Meerbeke, Alberto
Modragón, Alexandra
Barbosa G., Yenny C.
Como citar
Publicación:
Revista Palmas; Vol. 31 Núm. 2 (2010); 61-70
0121-2923
Revista Palmas; Vol. 31 Núm. 2 (2010); 61-70
0121-2923
Abstract
Scientific evidence about the possible harmful effects of palmolein (liquid fraction of palm oil) on human health is controversial. Some studies say that the saturated fats contained in this vegetable oil are associated with serum cholesterol and lipoprotein level elevation; but according to others it seems that palmolein has no harmful effect in normocholesterolemic human subjects with a normal fat diet. Objectives: Critically analyze the evidence from research about the effect of dietary palmolein on lipid profile (total cholesterol-tc, high and low-density lipoproteins-HDL, LDL) on normocholesterolemic individuals. Methodology: A systematic review of the literature was performed. Electronic databases (Medline, Ovid, EBSCOhost, Hinari, Bireme) were reviewed, including controlled clinical trials performed on humans from 1991-2007. Results: 256 studies were originally retrieved; 19 met the selection criteria entirely. In the 19 trials, 693 patients from 42 independent groups were evaluated. The outcome measures were the differences between blood lipid parameters before and after the diets with refined palm or other oils. It was observed that palm oil did not increase the basal levels of cholesterol and lipoproteins, and that it even had a positive effect on the ratio TC/HDL and HDL/LDL. Discussion: Blood lipid levels in pre- and post- palm oil diets were very similar to those in diets with olive oil and sunflower fats, traditionally considered beneficial to health. Existe una controversia en la evidencia científica de si la oleína de palma tiene o no un efecto nocivo sobre el perfil lipídico humano en individuos normocolesterolémicos. Objetivos: Analizar en forma crítica la evidencia disponible sobre el efecto en el perfil lipídico de la oleína de palma utilizada en individuos con colesterol normal (Colesterol total, lipoproteínas de alta y baja densidad). Metodología: Revisión sistemática de la literatura. Se revisaron bases de datos electrónicas (Medline, Ovid, EbscoHost, Hinari, Bireme) y se realizaron búsquedas manuales. Se incluyeron ensayos clínicos controlados en humanos desde 1991-2007 cuyo objetivo coincidiera con el planteado. Resultados: 256 estudios fueron recuperados inicialmente, 19 cumplían en su totalidad con criterios de inclusión, para un total de 693 pacientes evaluados en 42 grupos independientes. Como medidas de resultado se compararon diferencias entre parámetros de lípidos sanguíneos, antes y después de las dietas con aceite de palma refinado u otros aceites. Se observó que el aceite de palma no aumentó los niveles basales de colesterol ni sus fracciones e incluso tuvo efectos positivos sobre la relación CT/HDL y HDL/LDL. Discusión: Los resultados de los lípidos sanguíneos finales fueron similares a los basales, al comparar las dietas con aceite de palma con las de aceite de oliva o de girasol, grasas consideradas tradicionalmente como benéficas para la salud.
Scientific evidence about the possible harmful effects of palmolein (liquid fraction of palm oil) on human health is controversial. Some studies say that the saturated fats contained in this vegetable oil are associated with serum cholesterol and lipoprotein level elevation; but according to others it seems that palmolein has no harmful effect in normocholesterolemic human subjects with a normal fat diet. Objectives: Critically analyze the evidence from research about the effect of dietary palmolein on lipid profile (total cholesterol-tc, high and low-density lipoproteins-HDL, LDL) on normocholesterolemic individuals. Methodology: A systematic review of the literature was performed. Electronic databases (Medline, Ovid, EBSCOhost, Hinari, Bireme) were reviewed, including controlled clinical trials performed on humans from 1991-2007. Results: 256 studies were originally retrieved; 19 met the selection criteria entirely. In the 19 trials, 693 patients from 42 independent groups were evaluated. The outcome measures were the differences between blood lipid parameters before and after the diets with refined palm or other oils. It was observed that palm oil did not increase the basal levels of cholesterol and lipoproteins, and that it even had a positive effect on the ratio TC/HDL and HDL/LDL. Discussion: Blood lipid levels in pre- and post- palm oil diets were very similar to those in diets with olive oil and sunflower fats, traditionally considered beneficial to health.
Palabras clave:
aceite de palma
oleína de palma
colesterol
aceites vegetales
metabolismo de lípidos
nutrición humana
salud
aceite de palma
oleína de palma
colesterol
aceites vegetales
metabolismo de lípidos
nutrición humana
salud